長崎大学大学院 医歯薬学総合研究科 保健学専攻 看護実践科学分野
長崎大学医学部保健学科看護学専攻（基礎・成人・精神・老年看護学領域）
日本語
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English
長崎大学大学院 医歯薬学総合研究科 保健学専攻 看護実践科学分野
長崎大学大学院 医歯薬学総合研究科 保健学専攻 看護実践科学分野
長崎大学医学部保健学科看護学専攻（基礎・成人・精神・老年看護学領域）
長崎大学医学部保健学科看護学専攻（基礎・成人・精神・老年看護学領域）

Publication

  • Publication
  • Pulmonary Alveolar Proteinosis with Ulcerative Colitis
Internal medicine 57, 18, 2705 - 2708 (2018)
Pulmonary Alveolar Proteinosis with Ulcerative Colitis

著者

Noriho Sakamoto , Shota Nakashima , Hiroshi Ishimoto , Tomoyuki Kakugawa , Atsuko Hara , Hirokazu Yura , Takuto Miyamura , Seiko Nakamichi , Yasushi Obase , Yuji Ishimatsu , Hiroshi Mukae

カテゴリ

学術論文

Abstract

A 65-year-old Japanese man was referred to our hospital for the further assessment of cough and dyspnea. He had a history of ulcerative colitis for which he was receiving treatment. Chest computed tomography showed a crazy-paving pattern. His bronchoalveolar lavage fluid had a milky appearance, and a transbronchial lung biopsy specimen revealed acellular periodic acid-Schiff stain-positive bodies. The serum anti-granulocyte macrophage-colony stimulating factor (GM-CSF) antibody titer was elevated. The diagnosis was autoimmune pulmonary alveolar proteinosis (PAP). There are few reports of autoimmune PAP in patients with ulcerative colitis. Some reports suggest that PAP and inflammatory bowel disease might have a common pathogenesis involving the anti-GM-CSF antibody.